The ingestion of a combination of carbohydrates that use different intestinal transporters for absorption, carbohydrate delivery and oxidation can be increased. These increases are seen when a carbohydrate is ingested that uses SGLT1 for absorption and a secondary carbohydrate that uses a different transport system are ingested simultaneously. Increased oxidation is only seen when the SGLT1 dependent carbohydrate is ingested at high rates (1 g/min). Whereas previously it was believed that the maximum absolute oxidation rate of ingested carbohydrate oxidation was 1 g/min, recent studies with multiple transportable carbohydrates have reported values up to 1.75 g/min. The increased carbohydrate oxidation with multiple transportable carbohydrates was accompanied by increased fluid delivery and improved oxidation efficiency and thus the likelihood of gastrointestinal distress may be diminished. Studies have also demonstrated reduced fatigue and improved exercise performance with multiple transportable carbohydrates compared with a single carbohydrate. Therefore multiple transportable carbohydrates, ingested at high rates, can be beneficial during endurance sports where the duration of exercise is 2.5 h or more. Guidelines will have to be adjusted to take these findings into account.
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